5 thoughts on “Do Your Probiotics Actually Work? Ask Your Gut.

  1. Serena

    I’m interested in participating in this study, but what does it mean by “before” probiotics, if you consume them from food sources regularly? Does that mean first thing in the morning you take a sample, and then again after a day of eating them? Or is this study for people who don’t already eat probiotic foods and then eat them for two weeks and do another sample?

  2. Steven Weil

    Great project, I would love to participate, however some clarification of terminology is necessary. The project Ubiome is proposing is more accurately described as a study looking at the effects of live active cultures and fermented foods on the Microbiota. Live active cultures and fermented foods are not Probiotics, according to the scientific definition developed by the WHO/FAO in a 2001 consensus conference. A Probiotic is, by this definition, is ‘a live microorganism, when administered in adequate amounts, confers a health benefit to the host (human or animal). Probiotics also, should be identified and characterized from the Genus to the species to the strain level of taxonomy.

    Many commercially produced fermented foods may not contain live active cultures, but could have an affect on the microbiota non the less.

    An example of a experimental study looking at the effects of a probiotic on the microbiota is the following;

    Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea.
    Swidsinski A, Loening-Baucke V, Verstraelen H, Osowska S, Doerffel Y.
    Gastroenterology. 2008 Aug;135(2):568-79.

    The probiotic was Saccharomyces boulardii CNCM I-745 (USA trade name Florastor).

  3. Bryan Moore

    It takes weeks for lifestyle and food changes to be seen and stabilize in your micro biome. So I believe the “Before” sample would be ideal if it comes from someone prior to an intentional change in diet or begin using Probiotic pills. And the “After” should be weeks to months after the diet change. If you are not changing anything in your diet, then there should be similar results between two samples taken.

  4. Joe

    This is a much needed step. If only the FDA were on board. We need independent testing of all probiotic products on the over the counter market, with before use testing, then after one month on the probiotic, and one month after discontinuing the probiotic. Only then will we determine if the species actually attach and thrive in the intestine. It seems all we have right now, is claims by manufacturers, with no independent testing and verification.

    I’ve read that these probiotic pills don’t contain the proper enzymes to be recognized by the body and implant on the intestinal wall. So, this testing would tease out the truth. It is a much needed approach, and will move our understanding forward with what is working and what is not.


  5. too late for me now but how did study turn out? I make my own Kombuchu, eat yogurt, cheese, kefir, sauerkraut, kimchi, and take several different probiotics with each meal and your test said I have no Bifs or Lactobacillus compared to others. I am not alone I have learned. Genetics of blood type, FUT genes, HLADQ2/8 are contributing factors. I am now ramping up my probiotics, fermented foods and hoping for you to “detect something”.

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